H2PRO Formula Reference Materials

The H2PRO™ Probiotic Blend was developed by Dr. Alan S. Baumgarten from evidence-based review of the medical literature and professional experience to combine the health benefits of four well-researched strains of probiotic species that provide immune modulating and health condition specific benefits including:

  • Beneficial bacteria for the Gastrointestinal tract
  • Inhibit the growth of harmful bacteria in the Gastrointestinal tract
  • Prevent antibiotic associated diarrhea
  • Help manage Gastrointestinal symptoms including constipation, bloating and diarrhea
  • Fortify the immune system to help fight viral infections including colds and flu

H2PRO™ Probiotic Blend

Bonus! Our H2PRObiotic blend can benefit digestive health, immune health & respiratory health.

7 Billion CFU*
Lactobacillus acidophilus (NCFM) 2 Billion CFU
Lactobacillus paracasei (Lpc-37) 3 Billion CFU
Bifidobacterium lactis (Bi-07) 1 Billion CFU
Bifidobacterium lactis (Bl-04) 1 Billion CFU
*Colony Forming Units at the time of manufacturing

Clinical research supporting the specific H2PRO Immune Health and Bone & Joint Health probiotics species includes:

  • West NP, Horn PL, Pyne DB, Gebski VJ, Lehtinen SJ, Fricker PA, Cripps AW. Aug 2014. Probiotic supplementation for respiratory and gastrointestinal illness symptoms in healthy, physically active individuals. Clin Nutr, 33(4):581-7.
  • Hemalatha R, Ouwehand AC, Forssten SD, Babu Geddan JJ, Mamidi RS, Bhaskar V, Radhakrishna KV. May 2014. A Community-based Randomized Double Blind Controlled Trial of Lactobacillus paracasei and Bifidobacterium lactis on Reducing Risk for Diarrhea and Fever in Preschool Children in an Urban Slum in India. Eur J Nutr & Food Safety, 4(4):325-41.
  • Ringel-Kulka T, Palsson O, Maier D, Carroll I, Galanko JA, Leyer G, Ringel Y. 2011. Probiotic Bacteria: Probiotic Bacteria Lactobacillus acidophilus NCFM.and Bifidobacterium lactis Bi-07™ Versus Placebo or the Symptoms of Bloating in Patients With Functional Bowel Disorders – a Double-blind Study. J Clin Gastroenterol. 45: 518-525.
  • Leyer GJ, Li S, Mubasher ME, Reifer C, Ouwehand AC. 2009. Probiotic effects on cold and influenza-like symptom incidence and duration in children. Pediatrics 124: e172-e179.
  • Albertini B, Vitali B, Passerini N, Cruciani F, Di Sabatino M, Rodriguez L, Brigidi P. 2010. Development of microparticulate systems for intestinal delivery of Lactobacillus acidophilus and Bifidobacterium lactis . Eur J Pharm Sci. 40: 359-366.
  • Roessler A, Forssten SD, Glei M, Ouwehand AC, Jahreis G. 2011. The effect of probiotics on faecal microbiota and genotoxic activity of faecal water in patients with atopic dermatitis: A randomized, placebo-controlled study. Clin Nutr. 2011 Sep 30.
  • Paineau D, Carcano D, Leyer G, Darquy S, Alyanakian MA, Simoneau G, Bergmann JF, Brassart D, Bornet F, Ouwehand AC. 2008. Effects of seven potential probiotic strains on specific immune responses in healthy adults: a double-blind, randomized, controlled trial. FEMS Immunol Med Microbiol. 53: 107-113.
  • Ouwehand AC, Nermes M, Collado MC, Rautonen N, Salminen S, Isolauri E. Specific probiotics alleviate allergic rhinitis during the birch pollen season. World J Gastroenterol. 2009 15: 3261-3268.
  • Parvaneh K, Jamaluddin R, Karimi G, Erfani R. Effects of Probiotics Supplementation on Bone Mineral Content and Bone Mass Density-Review Article.” Scientific World Journal. 2014, 595962: 1-6.
  • Scholz-Ahrens KE, Ade P, Marten B, Weber P, Timm W, Asil Y, Gluer CC, Schrezenmeir J. “Prebiotics, probiotics and synbiotics affect mineral absorption, bone mineral content and bone structure”. J Nutr. 137; 838S-846S, 2007.

H2PRO Vitamin and Micronutrient Enhancements

The H2PRO vitamin and micronutrient enhancements have been specially selected by Dr. Alan S. Baumgarten from evidence-based review of the medical literature and professional experience to promote individual health and wellness. The vitamin and micronutrient formulations supplement daily intake and encourage higher levels of health and wellness for specific conditions.

A representative selection of clinical research supporting the specific H2PRO Immune and Bone & Joint Health vitamin and micronutrient enhancements includes:

  • Maggini S, Wenzaff S, Hornig, D. Essential Role of Vitamin C and Zinc in Child Immunity and Health.

Glucosamine & Chondroitin

  • Clegg D, et al. “Glucosamine, chondroitin sulfate and the two in combination for painful knee osteoarthritis.” N England J. International Medical Res, 2010; 386-414. Med. 2006 Feb 23;354(8): 795-808.
  • Bikle D. Vitamin D and Immune Function: Understanding Common Pathyways. Current Osteoporosis Reports, 2009; 7:58-63.
  • Newsholme P. Why is L-Glutamine Metabolism Important to Cells of the Immune System in Health, Post-Injury, Surgery and Infection? J of Nutrition, 2001; 131, 2515S-2522S.
  • Wernerman J., Herrero-Beaumont G et al. “Glucosamine sulfate in the treatment of knee osteoarthritis symptoms: a randomized double-blind, placebo controlled study using acetaminophen as a side comparator.” Arthritis Rheum. 2007 Feb;56(2):555-67.
  • Bruyere O, Reginster JY. “Glucosamine and chondroitin sulfate as therapeutic agents for knee and hip osteoarthritis.” Drugs Aging. 2007;24(7):573-80.
  • The National Center for Complementary and Alternative Medicine. ‘The NIH Glucosamine/Chondroitin Arthritis Intervention Trial (GAIT).” J Pain Palliat Care Pharmacother. 2008;22(1):39-43.
  • Sawitzke AD. “Clinical Use of Glutamine Supplementation. J of Nutrition, 2008; 138: 2040S-2044S.
  • Field CJ, Johnson I, Pratt VC. Glutamineefficacy and Arginine: Immunonutrients for Improved Health. Medicinesafety of glucosamine, chondroitin sulfate, and Science in Sports & Exercise, 2000; 32 (7 Supp): S377-88. their combination, celecoxib or placebo taken to treat osteoarthritis of the knee: 2-year results from GAIT.” AnnRheum Dis. 2010 Aug;69(8)1459-64.
  • Hochberg M, et al. Combined chondroitin sulfate and glucosamine for painful knee osteoarthritis: a multicenter, randomized, double-blind, non-inferiority trial versus celeoxib. Ann Rheum Dis doi:10.1136/2014.

Vitamin D

  • Cosman F, de Beur SJ, LeBoff MS et al. “Clinician’s guide to prevention and treatment of osteoporosis. Osteoporosis Int. 2014;25(10):2359-2381.
  • American Geriatrics Society Workgroup on Vitamin D Supplementation for Older Adults. “Recommendations abstracted from the American Geriatrics Society Consensus Statement on Vitamin D for of falls and their consequences.” J Am Geriatrics Soc. 2014: 62:147.
  • Institute of Medicine. “Report at a Glance, Report Brief: Dietary reference intakes for calcium and Vitamin D, released 11/30/2010. http//www.iom.edu.linproxy.lib.unc.edu?Reports/2010/Dietary-References-Intakes-for-Calcium-and-Vitamin-D/Report-Brief.aspx.

Calcium

  • Cosman F, de Beur SJ, LeBoff MS et al. “Clinician’s guide to prevention and treatment of osteoporosis. Osteoporosis Int. 2014;25(10):2359-2381.
  • Institute of Medicine. “Report at a Glance, Report Brief: Dietary reference intakes for calcium and Vitamin D, released 11/30/2010. http//www.iom.edu.linproxy.lib.unc.edu?Reports/2010/Dietary-References-Intakes-for-Calcium-and-Vitamin-D/Report-Brief.aspx
  • Sanders, KM, Nowson CA, Kotowicz MA, Briffa K, Devine A, Reid IR. “Calcium and bone health: position statement for the Australian and New Zealand Bone and Mineral Society, Osteoporosis Australia and the Endocrine Society of Australia.” Medical J Australia. 2009; 190(6): 316-320.

Magnesium

  • Castigalioni S, Cazzaniga A, Albisetti W, Maier JA. “Magnesium and osteoporosis-maintaining bone integrity.” Nutrients. 2013 Jul 31; 5(8):3022-33.
  • Cosman F, de Beur SJ, LeBoff MS et al. “Clinician’s guide to prevention and treatment of osteoporosis. Osteoporosis Int. 2014;25(10):2359-2381.